A Novel Approach to Preventing Migraine

A billion people in the world suffer from migraine headaches. New hints are

emerging that can help remedy that.

Migraines can be triggered by a number of factors. Many of them, it turns out, are

associated with mitochondrial function. And several nutrients that have been

suggested to protect against migraine are involved in mitochondrial function.

This well-designed study set out to see if getting enough of those nutrients could

play a role in the prevention of migraines.

The study followed 202,656 people who did not suffer from migraines for an

average of 13.25 years. Over that time, 0.9% of them were now diagnosed with

migraine.

The study measured dietary intake of 7 nutrients associated with mitochondrial

function: magnesium, B1, B2, B3, B6, B12 and folate.

The people who developed migraine had lower dietary levels of all 7 nutrients

and, especially, of niacin and B12.

This study suggests that getting more of these nutrients, perhaps especially

magnesium and, most importantly, B3 and B12, may help prevent migraine

headaches.

J Headache Pain. 2025 Nov 11;26(1):250.