Huge Study Demonstrates Spirulina’s Benefits for Cardiovascular Health

Cardiovascular disease is the leading cause of death in the world. One of the

tiniest supplements in nature could help the largest health problem in the world.

Cardiovascular disease includes coronary artery disease, angina, stroke, heart

attack and congestive heart failure. Important risk factors include high blood

pressure, cholesterol problems, diabetes, unhealthy diet and lifestyle, smoking,

excessive alcohol, inflammation, oxidative stress and obesity. Importantly, these

are, too a large extent, within our control. And, according to the American Heart

Association, the fundamental goal in preventing cardiovascular disease is

reducing these risk factors.

Spirulina, a blue-green microalgae, has the power to address many of these risk

factors. This meta-analysis set out to see just how well it can do it.

The meta-analysis included 35 controlled studies published between 2000 and

2024. Combined, the studies included 1,523 people.

The results showed that spirulina significantly lowered triglycerides, total

cholesterol and the unhealthy LDL cholesterol while raising the healthy HDL

cholesterol. It significantly lowered both systolic and diastolic blood pressure.

Spirulina also significantly reduced fasting blood glucose, insulin and insulin

resistance.

Both weight and body mass index were significantly improved by spirulina.

Markers of inflammation, including TNF-α, IL-6 and C-reactive protein, were all

significantly reduced.

If you look back at the risk factors that need to be controlled, you’ll notice that

spirulina controls almost all of them. Add that spirulina is powerfully antioxidant

and loaded in nutrients, including being a complete protein that is rich in essential

fatty acids; vitamins, including B12; and minerals, and it looks like a perfect fit for

preventing cardiovascular disease. Importantly, spirulina is also safe.

Complementary Therapies in Medicine. November 2025;94:103242.